| Individual adolescent factors | |
| Facilitative | Obstructive |
| Have knowledge about CC and HPV vaccine | Have less knowledge about CC and HPV vaccine |
| Try to get more information | |
| Have future self-image and visions | |
| Express fear and desire to escape from CC | Do not get a concrete picture of what CC really |
| Recognize the value of the HPV vaccine | Distrust the HPV vaccine |
| Have anxiety regarding IM injection | |
| Already have boyfriends | Do not have a boyfriend or have no plan to get a boyfriend |
| Be aware of slow sexual growth | |
| Discuss CC and HPV vaccine with their caregivers | Do not seriously discuss HPV vaccination with caregivers |
| Express willingness to accept HPV vaccination to their caregivers | |
| Prioritize the caregiver’s thinking on HPV vaccination | |
| Have psychological anguish | |
| Regularly visit the clinic | |
| Caregiver factors | |
| Facilitative | Obstructive |
| Have basic understanding about the effectiveness of HPV vaccination against CC | |
| Be aware of the increasing prevalence of CC in the Japanese younger generations | |
| Be deprived of the future childbearing opportunities due to CC | |
| Know that HPV vaccination was recommended before the start of sexual intercourse | |
| Have expectation for the effects of vaccination | Distrust the HPV vaccine |
| Have fears against cancer | |
| Adolescents have boyfriends | Adolescent girls did not have any boyfriends |
| Believe the adolescents had not yet had any sexual relationships | |
| Unilateral decision on the adolescents’ HPV vaccination | Respect the adolescents’ opinions |
| Feel difficult to explain HPV vaccine to the adolescents | |
| Feel embarrassed explaining the detail of sexual intercourse | |
| Adolescents have regularly visited the clinic | |
| Be trust in doctors’ recommendations for HPV vaccination | |
| Doctors’ responses to caregivers’ questions about HPV vaccination | |
| Easy to locate the hospital | |